MODELING UNSTIRRED DEAD-END ULTRAFILTRATI ON OF A SOLUTION OF BOVINE SERUM-ALBUMIN (BSA)

Unlike non-charged macromolecules and silts, the general unsteady stat e convection-diffusion equations associated with the osmotic theory do not allow accurate prediction of the ultrafiltration of bovine serum albumin (BSA) solutions in an unstirred cell. We postulate a modificat ion of the physicochemical properties of the solution in the boundary layer and attempt to simulate an experiment with a particular concentr ation evolution of the osmotic pressure. Afterwards, the use of these new data gives excellent results for all the other different experimen ts undertaken at a given pH.