Several amphiphilic glycosyl carbamates, glycosyl thiocarbamates and glycos
ylthioureas were prepared by addition of the anomeric hydroxyl group of ace
tylated glycosyl derivatives to alkyl isocyanates, or by reaction of glycos
yl isothiocyanates with alcohols or amines. The solubility, critical micell
e concentrations and detergent efficiency for the extraction of proteins of
these compounds were evaluated and compared. (C) 1999 Elsevier Science Ltd
. All rights reserved.