Solitary bone plasmacytoma: Management of isolated local relapse followingradiotherapy

Citation
Cr. Lewanski et al., Solitary bone plasmacytoma: Management of isolated local relapse followingradiotherapy, CL ONCOL-UK, 11(5), 1999, pp. 348-351
Citations number
12
Categorie Soggetti
Oncology
Journal title
CLINICAL ONCOLOGY
ISSN journal
09366555 → ACNP
Volume
11
Issue
5
Year of publication
1999
Pages
348 - 351
Database
ISI
SICI code
0936-6555(1999)11:5<348:SBPMOI>2.0.ZU;2-I
Abstract
Radiotherapy is the prime treatment modality for solitary plasmacytomas of bone (SPB). Although local control rates are excellent, progression to mult iple myeloma is frequent, albeit with varying latency. Local failure in the absence of dissemination is rare and thus management is poorly documented. We discuss such a patient who presented 3 years after local radiation for a pelvic SPB and review the relevant literature. Radiation doses, portals e mployed and prognostic factors that may predict progression to myeloma are discussed. This report shows that an isolated recurrence of SPB in a previo usly irradiated field was successfully treated with orthopaedic surgery. Th is resulted in good pain relief and mobility for the patient, who remains f ree of disease 6 months after operation.