Postitron emission tomography (PET) is emerging as a powerful tool that com
plements conventional radiologic studies in the evaluation of a variety of
thoracic abnormalities. PET is typically performed with the imaging agent F
DG, a glucose analog, which exploits differences in glucose metabolism betw
een normal and neoplastic cells, allowing accurate, noninvasive differentia
tion of benign from malignant abnormalities. This article focuses on the cu
rrent applications of FDG-PET in the thorax and reviews the evaluation of f
ocal pulmonary opacities, lung cancer staging, tumor recurrence, treatment
response, and prognosis.