Current biology of VEGF-B and VEGF-C

Authors
Olofsson, B Jeltsch, M Eriksson, U Alitalo, K
Citation
B. Olofsson et al., Current biology of VEGF-B and VEGF-C, CURR OPIN B, 10(6), 1999, pp. 528-535
Citations number
87
Categorie Soggetti
Microbiology
Journal title
CURRENT OPINION IN BIOTECHNOLOGY
ISSN journal
09581669 → ACNP
Volume
10
Issue
6
Year of publication
1999
Pages
528 - 535
Database
ISI
SICI code
0958-1669(199912)10:6<528:CBOVAV>2.0.ZU;2-G
Abstract
Endothelial growth factors and their receptors may provide important therap eutic tools for the treatment of pathological conditions characterised by d efective or aberrant angiogenesis. Vascular endothelial growth factor (VEGF ) is pivotal for vasculogenesis and for angiogenesis in normal and patholog ical conditions. VEGF-B and VEGF-C provide this gene family with additional functions, for example, VEGF-C also regulates lymphangiogenesis.