A limited understanding of the nature of chronic fatigue syndrome and fibro
myalgia has previously complicated the management of these disorders. Recen
t research has provided insights into their pathophysiology, as well as evi
dence for effective treatment. There is now reasonable research backing for
cognitive-behavioural therapy and graded exercise in chronic fatigue syndr
ome, whilst exercise and antidepressants offer some benefits in fibromyalgi
a. Curr Opin Psychiatry 12:727-732. (C) 1999 Lippincott Williams & Wilkins.