Transcriptional map of chromosome region 6q16 -> q21

We present the transcription map of chromosome region 6q16-->q21 by mapping fifteen known genes within this region. Five genes lay in the subregion co ntaining a tumor suppressor gene, eight genes are located in the subregion harboring a senescence gene, and two genes are distal to the latter region. The precise location of the genes was obtained using a previously describe d translocation and deletion mouse/human hybrid panel. An even more accurat e definition was possible for the genes spanning the senescence gene region , since a previously described YAC contig with its restriction map was avai lable. From this transcription map it is possible to derive a large region of synteny with mouse chromosome 10.