Uterine metastases from breast cancer in a patient under tamoxifen therapy. Case report

The authors report a case of metastases of breast cancer confined to the ut erus and cervical subserous leiomyoma in a postmenopausal woman under tamox ifen therapy for two years. After abnormal uterine bleeding, pathologic exa mination on biopsy of a cervical polyp revealed cervical involvement second ary to lobular breast cancer. The patient underwent total abdominal hystere ctomy with bilateral salpingo-oophorectomy. Pathologic examination of the s urgical specimen revealed both invasion of breast origin and of the cervix until the isthmus, endometrium and cervical subserous leiomyoma. The adnexa uteri were not affected. The possibility of uterine metastases in patients suffering from breast cancer, either undergoing tamoxifen therapy or not, always has to be considered.