Diagnosis of neonatal hemochromatosis with MR imaging and duplex Doppler sonography

Neonatal hemochromatosis is a rare congenital disorder which affects both f etuses and newborns. It is characterized by hepatocellular failure, often a ppearing on the first day of life in the form of coagulopathy, hypoalbumine mia, hypoglycemia, and jaundice. Most of the affected infants die early in life, and definitive diagnosis has often been made only by post-mortem eval uation. With the help of MRI, plus increasing awareness of the disorder, di agnosis is now often made early, even in utero. Duplex Doppler sonography d oes not provide information on siderosis but shows abnormalities in the liv er or blood-flow patterns associated with liver disease.