An Ni(chitin)(2) modified nitric oxide microsensor

The development of a simple, sensitive, selective, and stable amperometric nitric oxide microsensor is described. It is based on Ni(chitin), mediators immobilized on a platinum, Nafion modified electrode. The detection of NO is based on the Ni(chitin)(2) catalysis of NO oxidation at an anodic potent ial of +0.74V (vs. SCE). The catalytic peak current is linear for a NO conc entration in the range of 8.5 x 10(-8) mol/L to 1.5 x 10(-5) mol/L, with a correlation coefficient of 0.9992. The detection limit of the microsensor i s 5.0 x 10(-8) mol/L. It is suitable for the direct measurement of NO in bi ological systems.