Variations in response to topically applied ocular drugs (e.g. mydriat
ics and cycloplegics) and their possible aetiology have been studied p
reviously. It appears that individual patient differences, external in
fluencing factors and the characteristics of the particular drug may a
ll govern the response. One factor worthy of note in this regard is th
e possibility of variation in the drug volume instilled. Single-use ey
e drop containers known as Minims(R) are commonly used during ophthalm
ic diagnostic procedures. However, in this study the drop volume was s
hown to vary considerably, depending upon the angle at which the Minim
s(R) container was held, the particular drug and the number of drops p
reviously expelled from the unit. (C) 1997 The College of Optometrists
.