The evidence base on the cost-effectiveness of malaria control measures inAfrica

This review assesses the range and quality of the evidence base on the cost -effectiveness of malaria prevention and treatment in sub-Saharan Africa. F ourteen studies are reviewed, covering insecticide-treated nets, residual s praying, chemoprophylaxis far children, chemoprophylaxis or intermittent tr eatment for pregnant women, a hypothetical vaccine, and changing the first line drug for treatment. The available evidence provides some guidance to d ecision-makers. However, the potential to inform policy debates is limited by the gross lack of information on the costs and effects of many intervent ions, the very small number of cost-effectiveness analyses available, the l ack of evidence on the costs and effects of packages of measures, and the p roblems in generalizing or comparing studies that relate to specific settin gs and use different methodologies and outcome measures.