M. Roth et C. Mountjoy, Classification and diagnosis of the anxiety and depressive disorders and some implications for clinical practice and enquiry, HUM PSYCHOP, 14, 1999, pp. S60-S71
Citations number
37
Categorie Soggetti
Neurosciences & Behavoir
Journal title
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
145 patients diagnosed with a structured interview as 'depressive illness'
or 'anxiety disorder' were submitted to multivariate analyses which yielded
a bimodal distribution corresponding to the anxiety and depressive disorde
rs, respectively. As anxiety and depressive profiles were negatively correl
ated to a significant extent, they were mutually exclusive with some overla
p, rather than independent. In a further analysis with seven well validated
rating scales 117 patients with anxiety disorder, agoraphobia and neurotic
depression alone were not studied. Statistical analysis separated clinical
profiles of anxiety and depressive disorders with some overlap. Complete s
eparation was achieved with discriminant function analysis. Some individual
anxiety and depression scales on their own achieved this separation. Clust
ers of childhood emotional and behavioural traits proved capable to some ex
tent of predicting the disorder to be manifest in the adult stage in both s
exes. But only in females was the form of illness into which patients devel
oped as adults (anxiety or depression) correctly predicted (88%) from child
hood traits to a highly significant degree. Copyright (C) 1999 John Wiley &
Sons, Ltd.