This work examines the use of single response surface (SRS) and multiple re
sponse surface (MRS) techniques for modeling spatial nonuniformity in semic
onductor applications. Previous works halve suggested that the MRS estimati
on techniques better measure the nonuniformity due to the underlying spatia
l function of the process, whereas SRS estimation methods measure the tc,ta
l process nonuniformity (systematic spatial nonuniformity plus random site
nonuniformity). This work further highlights this fact in an analytical set
ting. It is demonstrated that the MRS estimation technique is biased and th
at this bias can lead to the choice of a nonoptimal process. Experimental d
ata from a chemical-mechanical polishing (CMP) process confirms these obser
vations and demonstrates that careful use of the MRS estimator is required
in achieving meaningful results for estimating spatial nonuniformity, Modif
ied versions of each method, which measure spatial nonuniformity alone, as
well as versions which measure total nonuniformity, are proposed for the ca
se when one is comparing discrete process settings. Analytical expressions
for the expected value and variance of both the SRS and MRS estimators are
determined. These are used to compare the efficiency (estimator variance) o
f these modified estimators. When comparing spatial nonuniformity, it is fo
und that the unbiased MRS estimator is more efficient than the SRS estimato
r modified to measure spatial nonuniformity. However, it is shown that the
MRS estimator, when modified to measure total nonuniformity, is not necessa
rily more efficient than the SRS method. Finally, the: continuous response
surface modeling case is considered, It is demonstrated how confidence inte
rvals on the underlying continuous site models lead to a nonuniform bias in
the response surface generated by the MRS method. This suggests that care
must be taken when using the MRS technique in creating continuous response
surfaces of spatial nonuniformity as a function of the process settings.