Classification, pharmacology, and side-effects of common laxatives

Authors
Muller-Lissner, S
Citation
S. Muller-lissner, Classification, pharmacology, and side-effects of common laxatives, ITAL J GAST, 31, 1999, pp. S234-S237
Citations number
22
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
ISSN journal
11258055 → ACNP
Volume
31
Year of publication
1999
Supplement
3
Pages
S234 - S237
Database
ISI
SICI code
1125-8055(199911)31:<S234:CPASOC>2.0.ZU;2-O
Abstract
No definition of the term laxative is satisfactory since their mode of acti ons affects multiple mechanisms, absorption/secretion and motor activity: L axatives are very heterogeneous chemically. They act by either holding wate r inside the bowel lumen (dietary fibre, osmotic laxatives), by inhibition of water absorption or stimulation of secretion (stimulation laxatives), ol by stimulation of colonic motility (stimulant laxatives, 5HT(4) agonists). Most laxatives have side-effects but these ape usually mild.