A new purine derivative, 6-methoxy-7-methyl-8-oxoguanine (1), along with 8-
oxoadenine (2) and the human metabolite S-methylxanthine (3), has been isol
ated from the ascidian Symplegma rubra collected on the southeastern coastl
ine of Brazil. The structures of the three purines were established by anal
ysis of spectroscopic data.