Cardiac troponin I in patients with myocardial infarction. Time course of its content in blood and relation to the volume of necrosis

Dynamics of cardiac troponin I was compared with those of creatine kinase, lactate dehydrogenase and aspartate aminotransferase in 25 patients with Q- wave and 25 - with non-Q-wave myocardial infarction. Blood levels of tropon in were correlated with location of infarction and volume of myocardial nec rosis. Concentration of troponin I was elevated in all patients. This eleva tion became obvious in several hours after onset of infarction (not later t han in 5-6 hours) and persisted for 4-12 days (mean 8-9 days). The level of troponin in blood serum depended on the volume of necrosis.