Sebaceous hyperplasia of the lower eyelid

Background Patient: A 61-year-old man was evaluated for a yellow tumor loca ted at the lid margin of his lower eyelid, which had recurred for the secon d time after surgical excision. The patient's ocular examination was otherw ise unremarkable as was the general examination with the exception of the p resence of a polyp in the colon and a family history of multiple colorectal carcinomas. The eyelid tumor was excised and histologic examination showed a sebaceous hyperplasia. Conclusion When one encounters a sebaceous tumor involving the eyelid the p ossibility of Muir-Torre syndrome should be considered. Muir-Torre syndrome is an autosomal dominant genodermatosis characterized by at least a single sebaceous gland tumor (either a hyperplasia, an adenoma, an epithelioma, o r a carcinoma) and a minimum of one internal malignancy.