Sequence similarities between human bornavirus isolates and laboratory strains question human origin

Authors
Schwemmle, M Jehle, C Formella, S Staeheli, P
Citation
M. Schwemmle et al., Sequence similarities between human bornavirus isolates and laboratory strains question human origin, LANCET, 354(9194), 1999, pp. 1973-1974
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9194
Year of publication
1999
Pages
1973 - 1974
Database
ISI
SICI code
0140-6736(199912)354:9194<1973:SSBHBI>2.0.ZU;2-S
Abstract
Human bornavirus RW98, whose genome differs by 3-4% from previous isolates, is almost identical to a rat-adapted laboratory strain. Other human bornav iruses are also strongly related to virus strains frequently used for exper iments in the various laboratories reporting human bornavirus, questioning a human origin of isolates known to date.