POPULATION DEMOGRAPHIC-STRUCTURE IN THE K URSKAYA OBLAST - ISOLATION BY DISTANCE

The population of the Kurskaya oblast (administrative region) was desc ribed using the Malecot's model of isolation by distance, Differences in inbreeding level between populations of raions (districts) were fou nd; the differences were determined by degrees of urbanization, age, a nd effective size of the populations, In the center of the oblast, an area was found with the minimum mean square distance between birthplac es of spouses, low effective migration pressure, and high isolation by distance, In populations of raions, a relationship was found between population inbreeding level and incidences of congenital malformations (CM) and multiple congenital malformations (MCM), which affected tile viability of infants.