If the loop fits ...

Authors
Frankel, AD
Citation
Ad. Frankel, If the loop fits ..., NAT ST BIOL, 6(12), 1999, pp. 1081-1083
Citations number
34
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NATURE STRUCTURAL BIOLOGY
ISSN journal
10728368 → ACNP
Volume
6
Issue
12
Year of publication
1999
Pages
1081 - 1083
Database
ISI
SICI code
1072-8368(199912)6:12<1081:ITLF.>2.0.ZU;2-Q
Abstract
The structure of the yeast L30 ribosomal protein bound to its autoregulator y RNA site has been determined by NMR spectroscopy. The intricate architect ure of the RNA internal loop and the structure of the binding region of the protein both are stabilized in the complex; highlighting the importance of mutually-induced fit in RNA-protein interactions.