Most medical cost-effectiveness analyses include future costs only for
related illnesses, but this approach is controversial. This paper dem
onstrates that cost-effectiveness analysis is consistent with lifetime
utility maximization only if it includes all future medical and non-m
edical expenditures. Estimates of the magnitude of these future costs
suggest that they may substantially alter both the absolute and relati
ve cost-effectiveness of medical interventions, particularly when an i
ntervention increases length of life more than quality of life. In old
er populations, current methods overstate the cast-effectiveness of in
terventions which extend life compared to interventions which improve
the quality of life.