Genetics and molecular biology of deafness

Citation
Km. Grundfast et al., Genetics and molecular biology of deafness, OTOLAR CLIN, 32(6), 1999, pp. 1067
Citations number
39
Categorie Soggetti
Otolaryngology
Journal title
OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA
ISSN journal
00306665 → ACNP
Volume
32
Issue
6
Year of publication
1999
Database
ISI
SICI code
0030-6665(199912)32:6<1067:GAMBOD>2.0.ZU;2-X
Abstract
With increased emphasis on early detection of hearing impairment, more babi es are likely to be referred at younger ages to otolaryngologists for evalu ation. With a diminution in the number of infants who have hearing impairme nt as a result of such factors as maternal infection, neonatal sepsis, or o totoxicity, the relative importance of detecting a genetic cause of newborn hearing impairment is likely to increase. Therefore, the otolaryngologist must become familiar with common causes of:hereditary hearing impairment an d the ways in which the newborn should be evaluated for hereditary hearing impairment. Advancements are rapidly being made in the ability to detect ge nes that cause hearing impairment, and we are now on the threshold of disco vering ways to use gene therapy to prevent or treat hereditary deafness.