Body growth was studied in 32 subjects with vesicoureteric reflux (VUR), di
agnosed following the prenatal finding of urinary tract dilatation, who had
normal renal filtration function and who received antibacterial prophylaxi
s by the first few days of life. They were followed for 1-5 years (mean 2.3
years). Most had persistent VUR during the Ist year of life. Body growth p
erformance was compared with that of 94 subjects with VUR diagnosed and tre
ated by us after the neonatal period. During the follow-up period, none of
the patients with prenatally detected VUR had a height Z score below -2, no
r a weight-for-height index below 90%, and 1 had variations in height Z sco
re ii. The difference in the percentage of patients with prenatally detecte
d VUR (1/32) and those with VUR diagnosed and treated after the neonatal pe
riod (20/94) who had variations in height Z score greater than or equal to
1 was significant (P=0.035), Patients with prenatally detected VUR and norm
al renal filtration function, given antibacterial prophylaxis by the first
few days of life, have normal body growth, although VUR still persists.