Amiodarone-induced pulmonary toxicity

Citation
Z. Kanji et al., Amiodarone-induced pulmonary toxicity, PHARMACOTHE, 19(12), 1999, pp. 1463-1466
Citations number
19
Categorie Soggetti
Pharmacology
Journal title
PHARMACOTHERAPY
ISSN journal
02770008 → ACNP
Volume
19
Issue
12
Year of publication
1999
Pages
1463 - 1466
Database
ISI
SICI code
0277-0008(199912)19:12<1463:APT>2.0.ZU;2-C
Abstract
Amiodarone-induced pulmonary toxicity (AIPT) is one of the most serious adv erse effects of amiodarone therapy and can be fatal. Therefore, vigilant mo nitoring is advised. Baseline chest radiograph and pulmonary function tests and follow-up chest films at 3-month intervals are advocated. However, sin ce abnormalities on these two examinations do not always precede symptoms, patient self-reports of respiratory symptoms appear to be the best method f or early detection of AIPT.