SILENT PERIOD IN UPPER-LIMB MUSCLES AFTER NOXIOUS CUTANEOUS STIMULATION IN MAN

We studied the effect of electrical stimulation of the C5-C8 dermatome s on voluntary electromyographic activity (EMG) recorded from the ipsi lateral first dorsal interosseus (FDI), abductor digiti minimi, flexor and extensor carpi, triceps brachii, biceps brachii, and orbicularis oculi muscles of healthy humans. Finger stimulation (C6-C8) produced a n EMG inhibition (silent period, SP), which progressively decreased in duration from distal to proximal muscles; in the biceps it induced a slight facilitation and in the orbicularis oculi muscle, it had no eff ect. Stimulation of the C5 dermatome induced no response in either dis tal or proximal muscles. Only high-intensity stimuli evoked clear sile nt periods. The threshold for evoking an SP was almost double that req uired for sensory action potentials, 3.25 times the sensory threshold, and decidedly above the pain threshold. An indirect estimation of the conduction velocity of SP afferent fibres placed them in the A-delta group of myelinated fibres. In double-shock experiments, used to study the recovery cycle of the SP in the FDI muscle after finger stimulati on, neither low- nor high-intensity conditioning stimuli delivered 100 -500 ms before the test stimulus changed test SPs. Experiments designe d to evaluate motoneuronal excitability showed that in relaxed FDI mus cle, finger stimulation markedly reduced the F wave at the 50 ms time interval, the time when the SP normally occurs. Our findings demonstra te that the activation of A-delta afferents from the fingers inhibits the C7-T1 motoneurons postsynaptically, through an oligosynaptic spina l circuit. We propose that the strong inhibitory effect exerted by nox ious cutaneous stimuli on all distal muscles may contribute to a defen ce action which is specific for the human upper limb. (C) 1997 Elsevie r Science Ireland Ltd.