DECREASED ANTERIOR CINGULATE GYRUS METABOLIC-RATE IN SCHIZOPHRENIA

Authors
HAZNEDAR MM BUCHSBAUM MS LUU C HAZLETT EA SIEGEL BV LOHR J WU J HAIER RJ BUNNEY WE
Citation
Mm. Haznedar et al., DECREASED ANTERIOR CINGULATE GYRUS METABOLIC-RATE IN SCHIZOPHRENIA, The American journal of psychiatry, 154(5), 1997, pp. 682-684
Citations number
13
Categorie Soggetti
Psychiatry,Psychiatry
Journal title
The American journal of psychiatry → ACNP
ISSN journal
0002953X
Volume
154
Issue
5
Year of publication
1997
Pages
682 - 684
Database
ISI
SICI code
0002-953X(1997)154:5<682:DACGMI>2.0.ZU;2-R
Abstract
Objective: This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia. Method: Fifty unmedicated male schizophrenic patients and 24 normal men were studied with posit ron emission tomography. Results: Compared with the normal men, the sc hizophrenic patients had lower relative metabolic rates in the anterio r cingulate and higher rates in the posterior cingulate. Conclusions: The findings suggest hypofunction in the anterior cingulate cortex in schizophrenia.