Synthesis of perhydrooxazinones from 2-aza-3-trimethylsilyloxy-1,3-butadiene. A general route to 3,3-disubstituted-beta-hydroxy acids

Citation
E. Bandini et al., Synthesis of perhydrooxazinones from 2-aza-3-trimethylsilyloxy-1,3-butadiene. A general route to 3,3-disubstituted-beta-hydroxy acids, SYNLETT, (11), 1999, pp. 1735-1738
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
11
Year of publication
1999
Pages
1735 - 1738
Database
ISI
SICI code
0936-5214(199911):11<1735:SOPF2>2.0.ZU;2-B
Abstract
1-Phenyl-2-aza-3-trimethylsilyloxy-1,3-butadiene reacts with aliphatic, aro matic and cyclic ketones to give in good to excellent yields 6,6-disubstitu ted-1,3-perhydro-oxazin-4-ones which, in turn, have been readily converted into beta -hydroxy carboxylic acids.