Synthesis and antitumor activity of puupehedione and related compounds

Authors
Barrero, AF Alvarez-Manzaneda, EJ Chahboun, R Cortes, M Armstrong, V
Citation
Af. Barrero et al., Synthesis and antitumor activity of puupehedione and related compounds, TETRAHEDRON, 55(52), 1999, pp. 15181-15208
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
52
Year of publication
1999
Pages
15181 - 15208
Database
ISI
SICI code
0040-4020(199912)55:52<15181:SAAAOP>2.0.ZU;2-E
Abstract
The first enantiospecific synthesis of bioactive marine puupehedione (2) an d related compounds from (-)-sclanol (11) is reported. The antitumor activi ty of these compounds was assayed and compared with that of the natural pro ducts. (C) 1999 Elsevier Science Ltd. All rights reserved.