Amphidinolide U, novel 20-membered macrolide from marine dinoflagellate Amphidinium sp.

Authors
Tsuda, M Endo, T Kobayashi, J
Citation
M. Tsuda et al., Amphidinolide U, novel 20-membered macrolide from marine dinoflagellate Amphidinium sp., TETRAHEDRON, 55(51), 1999, pp. 14565-14570
Citations number
9
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
51
Year of publication
1999
Pages
14565 - 14570
Database
ISI
SICI code
0040-4020(199912)55:51<14565:AUN2MF>2.0.ZU;2-H
Abstract
A novel 20-membered macrolide, amphidinolide U (1), has been isolated from a marine dinoflagellate Amphidinium sp. and the structure was elucidated on the basis of spectroscopic data. The relative stereochemistry of C-15, C-1 8, and C-19 was deduced from NOESY correlations, while the absolute configu rations at C-8 and C-24 were assigned as both S on the basis of modified Mo sher's method. (C) 1999 Elsevier Science Ltd. All rights reserved.