Absolute stereostructures of novel cytotoxic metabolites, penostatins A-E,from a Penicillium species separated from an Enteromorpha alga

Authors
Iwamoto, C Minoura, K Oka, T Ohta, T Hagishita, S Numata, A
Citation
C. Iwamoto et al., Absolute stereostructures of novel cytotoxic metabolites, penostatins A-E,from a Penicillium species separated from an Enteromorpha alga, TETRAHEDRON, 55(50), 1999, pp. 14353-14368
Citations number
17
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
50
Year of publication
1999
Pages
14353 - 14368
Database
ISI
SICI code
0040-4020(199912)55:50<14353:ASONCM>2.0.ZU;2-U
Abstract
Penostatins A - E have been isolated tom a strain of Penicillium sp. origin ally separated tom the marine alga Enteromorpha intestinalis, and their abs olute stereostructures and conformations have been established on the basis of spectral analyses and some chemical transformations. All the compounds except for penostatin D exhibited significant cytotoxicity against cultured P388 cells. (C) 1999 Elsevier Science Ltd. All rights reserved.