Synthesis of key intermediates for a concise and convergent approach to the marine natural product eleutherobin

Authors
Baron, A Caprio, V Mann, J
Citation
A. Baron et al., Synthesis of key intermediates for a concise and convergent approach to the marine natural product eleutherobin, TETRAHEDR L, 40(52), 1999, pp. 9321-9324
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
52
Year of publication
1999
Pages
9321 - 9324
Database
ISI
SICI code
0040-4039(199912)40:52<9321:SOKIFA>2.0.ZU;2-C
Abstract
Synthesis of 1,6-syn-5,6-anti-2-methyl-5-isopropyl-bicyclo[4.3.0]non-2-en-8 -one in three steps from (rac)-phellandrene; and 1,6-syn-1-methyl-6-methoxy -3-aza-9-oxabicyclo[4.2.1]non-7-en-4-one in five steps from 2-methoxy-5-met hylfuran and tetrabromoacetone, provided these key intermediates for the co nstruction of the skeleton of eleutherobin. (C) 1999 Elsevier Science Ltd. All rights reserved.