The first synthesis of a 2 ',3 '-methane carbocyclic nucleoside

Authors
Katagiri, N Yamatoya, Y Ishikura, M
Citation
N. Katagiri et al., The first synthesis of a 2 ',3 '-methane carbocyclic nucleoside, TETRAHEDR L, 40(51), 1999, pp. 9069-9072
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
51
Year of publication
1999
Pages
9069 - 9072
Database
ISI
SICI code
0040-4039(199912)40:51<9069:TFSOA2>2.0.ZU;2-R
Abstract
A 2',3'-methano carbocyclic nucleoside, 9-(c-4-hydroxymethylbicyclo[3.1.0]h ex-r-2-yl)-9H-adenine, has been efficiently synthesized from 2-azabicyclo[2 .2.1]hex-5-en-3-one(ABH) in six steps involving 1,3-dipolar cycloaddition, photolysis, and adenine ring construction, (C) 1999 Elsevier Science Ltd. A ll rights reserved.