OBJECTIVE. The purpose of this study was to determine the MR findings
in patients with giant cell tumors of the tendon sheath. MATERIALS AND
METHODS. MR imaging findings in nine surgically proved cases of giant
cell tumors of the tendon sheath were evaluated on both T1- and T2-we
ighted images. Of nine lesions, three involved the foot, two involved
the thumb, two involved the knee, one involved the proximal part of th
e tibia, and one involved the proximal part of the femur. RESULTS. All
nine lesions were hypointense on T1-weighted images; the signal inten
sity of most of the tumors was approximately equal to that of skeletal
muscle. On the T2-weighted images, three lesions were hypointense rel
ative to skeletal muscle, two lesions were approximately isointense re
lative to skeletal muscle, and two lesions were slightly hyperintense
relative to skeletal muscle but hypointense relative to fat. The remai
ning two lesions had a more heterogeneous appearance on T2-weighted im
ages. CONCLUSION. On both T1- and T2-weighted images, giant cell tumor
of the tendon sheath has a signal intensity similar to that of its pa
thologic counterpart, pigmented villonodular synovitis. The decreased
signal intensity on both T1- and T2-weighted images is an uncommon app
earance of extraarticular soft-tissue masses, in particular when they
occur in the hands or feet, and this may suggest the diagnosis of gian
t cell tumor of the tendon sheath.