Synthesis of 3-deoxy-3,3-difluoroshikimic acid and its 4-epimer from quinic acid

Authors
Jiang, S Singh, G Boam, DJ Coggins, JR
Citation
S. Jiang et al., Synthesis of 3-deoxy-3,3-difluoroshikimic acid and its 4-epimer from quinic acid, TETRAHEDR-A, 10(21), 1999, pp. 4087-4090
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
21
Year of publication
1999
Pages
4087 - 4090
Database
ISI
SICI code
0957-4166(19991029)10:21<4087:SO3AAI>2.0.ZU;2-1
Abstract
3-Deoxy-3,3-difluoroshikimic acid 2 and its 4-epimer 3 as new analogues of shikimic acid have been synthesised from quinic acid in overall yields of 3 0% and 12%, respectively. (C) 1999 Elsevier Science Ltd. All rights reserve d.