Carbacylamidophosphates: Structure and properties of bis(N,N '-morpholido)-[(N ''-morpholido)-carboxamido] phosphate

The bis(N,N'-morpholido)-[(N"-morpholido)-carboxamido] phosphate: O(CH2CH2) NC(O)-N(H)P(O) [N(CH2CH2)O](2) [HL], has been prepared and characterized by means of IR, P-31 and H-1 NMR spectroscopy and X-ray diffraction (triclini c, a = 9.282(2), b = 9.308(2), c = 21.341(4) Angstrom, alpha = 80.79(3)degr ees, beta = 80.92(3)degrees gamma = 66.92(3)degrees, V = 1665.1(6) Angstrom (3), space group P (1) over bar, Z = 4 and R = 0.0423, wR2 = 0.1303 for 677 4 unique reflections used). The unit cell consists of two independent molec ules connected by hydrogen bonds N-H...O=P into non-symmetric dimers. The c ompound behaves as a HL molecule with a protonation constant corresponding to the -C(O)N(H)P(O)- group of pK = 8.65 as determined by potentiometric st udies.