Necrobiosis lipoidica - A case with prominent cholesterol clefting and transepithelial elimination

Citation
C. De La Torre et al., Necrobiosis lipoidica - A case with prominent cholesterol clefting and transepithelial elimination, AM J DERMAT, 21(6), 1999, pp. 575-577
Citations number
12
Categorie Soggetti
Dermatology
Journal title
AMERICAN JOURNAL OF DERMATOPATHOLOGY
ISSN journal
01931091 → ACNP
Volume
21
Issue
6
Year of publication
1999
Pages
575 - 577
Database
ISI
SICI code
0193-1091(199912)21:6<575:NL-ACW>2.0.ZU;2-8
Abstract
Transepithelial elimination of degenerated collagen through the hair follic le in necrobiosis lipoidica is rare, clinically manifesting as comedo-like plugs. Also unusual in necrobiosis Lipoidica is the finding of cholesterol cleft formation. We report a case of necrobiosis lipoidica with transepithe lial elimination of cholesterol crystals through hair follicles. This has b een described in necrobiotic xanthogranuloma, demonstrating some overlap in the histopathologic findings in both necrobiotic granulomas. Additional cr iteria should be used to establish the diagnosis.