C. De La Torre et al., Necrobiosis lipoidica - A case with prominent cholesterol clefting and transepithelial elimination, AM J DERMAT, 21(6), 1999, pp. 575-577
Transepithelial elimination of degenerated collagen through the hair follic
le in necrobiosis lipoidica is rare, clinically manifesting as comedo-like
plugs. Also unusual in necrobiosis Lipoidica is the finding of cholesterol
cleft formation. We report a case of necrobiosis lipoidica with transepithe
lial elimination of cholesterol crystals through hair follicles. This has b
een described in necrobiotic xanthogranuloma, demonstrating some overlap in
the histopathologic findings in both necrobiotic granulomas. Additional cr
iteria should be used to establish the diagnosis.