Citation
Ja. Talwalkar et al., Severe cholestasis related to itraconazole for the treatment of onychomycosis, AM J GASTRO, 94(12), 1999, pp. 3632-3633
Citations number
4
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
AMERICAN JOURNAL OF GASTROENTEROLOGY
ISSN journal
00029270
→ ACNP
Volume
94
Issue
12
Year of publication
1999
Pages
3632 - 3633
Database
ISI
SICI code
0002-9270(199912)94:12<3632:SCRTIF>2.0.ZU;2-1
Abstract
We describe a case of prolonged cholestasis temporally associated with the
use of itraconazole for onychomycosis. Peak bilirubin level of 32.0 mg/dl w
as documented approximately 2 months after discontinuation of the patient's
itraconazole therapy, with symptoms of cholestasis persisting more than 1
month after the peak in bilirubin. Physicians should be aware of the potent
ial for severe cholestasis associated with itraconazole usage. (Am J Gastro
enterol 1999;94:3632-3633. (C) 1999 by Am. Coll. of Gastroenterology).