Porcine Escherichia coli diarrhoea and oedema disease: pathogenesis and identification of genetic resistant breeding stack

Postweaning Escherichia (E.) coli diarrhoea and oedema disease art highly c ontagious endemic diseases. This review concentrates on current knowledge a bout adhesion of pathogenic bacteria to the mucosa of the small intestine, production of toxin(s) and the resulting disease in the pig. The mutation a t basepair 307 in the alpha(1,2) fucosyltransferasel (FUT1(M307)) gene whic h controls with high certainty resistance and susceptibility to E. coli F18 adhesion will be described and, furthermore, its use for marker-assisted s election is discussed.