Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance

We have sought to test the possibility of detecting regions of the genome u nder selection through effects on variation at linked neutral genetic marke rs. Particularly, we investigated three genomic regions identified by mappi ng in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolerance . Population genetic analysis is used with mapped microsatellites to try to infer selection for trypanotolerance in West African cattle populations.