alpha-neurotoxins and alpha-conotoxins, blockers of nicotinic acetylcholine receptors

Authors
Utkin, YN Kasheverov, IE Tsetlin, VI
Citation
Yn. Utkin et al., alpha-neurotoxins and alpha-conotoxins, blockers of nicotinic acetylcholine receptors, BIOORG KHIM, 25(11), 1999, pp. 805-810
Citations number
54
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANICHESKAYA KHIMIYA
ISSN journal
01323423 → ACNP
Volume
25
Issue
11
Year of publication
1999
Pages
805 - 810
Database
ISI
SICI code
0132-3423(199911)25:11<805:AAABON>2.0.ZU;2-O
Abstract
The review is devoted to the competitive blockers of different nicotinic ac etylcholine receptors, alpha-neurotoxins from snake venoms, and alpha-conot oxins from marine snails of the Conidae family. The relationship between th e structure and function of these toxins is discussed. Recent data on the m echanism of alpha-neurotoxin and alpha-conotoxin interaction with the nicot inic acetylcholine receptor are presented.