Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome

Authors
Aktas, D Koc, A Boduroglu, K Hicsonmez, G Tuncbilek, E
Citation
D. Aktas et al., Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome, CANC GENET, 116(1), 2000, pp. 44-46
Citations number
20
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608 → ACNP
Volume
116
Issue
1
Year of publication
2000
Pages
44 - 46
Database
ISI
SICI code
0165-4608(20000101)116:1<44:MSAWM7>2.0.ZU;2-3
Abstract
Bloom syndrome is a genomic instability syndrome associated with predisposi tion to development of various types of malignancy. In this report, rye des cribed a 7-year-old boy with Bloom syndrome (BS) and myelodysplastic syndro me (MDS) associated with monosomy 7 and loss of the Y chromosome. To our kn owledge, this was the first case with BS showing monosomy 7 and MDS during the early childhood period. (C) 1999 Elsevier Science Inc., 1999. All right s reserved.