THE RELATIONSHIP BETWEEN JUXTAPAPILLARY DUODENAL DIVERTICULA AND BILIARY STONE DISEASE

Objective: To assess the relationship between juxtapapillary duodenal diverticula (IDD) and common bile duct stones and biliary stone diseas e in general. Design: A retrospective study. Methods: We analysed 1115 patients who underwent consecutive endoscopic retrograde cholangiopan creatography examinations. The patients were subdivided into three gro ups: the first group (group 1; n = 482) had no biliary stone disease, the second one (group II; n = 329) had common bile duct stones, and th e third group (group III; n = 304) had biliary stone disease of the ga llbladder but without evidence of common bile duct stones. Additionall y, the patients were subdivided into age groups of < 50, 50-59, 60-69, 70-79, and greater than or equal to 80 years of age. Logistic regress ion was applied for statistical analysis. Results: Juxtapapillary duod enal diverticula were diagnosed in 111 (10.0%) patients. The incidence of JDD was 6.9% in group I, 14.3% in group II and 10.2% in group III. Age was the most dominant influence factor for DD, common bile duct s tones, and biliary stone disease (P < 0.0001). Sex was also a factor, female patients having a higher risk for common bile due; stones (P = 0.01) and biliary stone disease (P < 0.0001). After adjustment for age and sex, JDD was found to have a noticeable, but not statistically si gnificant (P = 0.073), influence on common bile duct stones and no inf luence on biliary stone disease (P = 0.15). Conclusion: Our data suppo rt only moderately the existence of a relationship, which had been con jectured in a part of the literature, between JDD and common bile duct stones. No noticeable influence on biliary stone disease was found.