Inflammatory myofibroblastic tumor with extensive involvement of the bowelin a 7-year-old child

We present a case of unusual localization of inflammatory fibroblastic tumo r in the terminal ileum, cecum, and ascending colon in a 7-year-old child. Segmental resection of the terminal ileum, cecum, and ascending colon with a tumor mass up to 6 cm in diameter was performed. Pathohistological examin ation of biopsy specimen was performed on routine hematoxylin-eosin section s, as well as immunohistochemically with primary antibodies to CD3, CD20, C D68, factor VIII, vimentin, smooth muscle actin, desmin, cytokeratin and S- 100 protein, and kappa and lambda light chains. The tumor was composed of h ighly vascularized tissue with interlacing fascicles of elongated spindle c ells admired with plasma cells, histiocytes, lymphocytes, and eosinophils. The diagnosis of inflammatory myofibroblastic tumor was confirmed by immuno histochemistry. Inflammatory myofibroblastic turner cannot be distinguished clinically from highly malignant neoplasm or some other conditions. Surgic al resection and careful pathohistological analysis are needed, and a long- term follow-up is recommended.