Cytologically, prokaryotes appear simpler and thus evolutionarily 'older' t
han eukaryotes. In terms of RNA processing, however, prokaryotes are sophis
ticated and eukaryotes, which retain many features of an RNA-world, appear
primitive. The last universal common ancestor may have been mesophilic and
could have had many features of the eukaryote genome, but its cytology is u
nknown.