INTRODUCTION: The use of retrograde irrigation enemas is common in the trea
tment of chronic constipation, especially in the elderly. Perforation of th
e rectum and sigmoid colon caused by cleansing enemas, used by chronically
constipated patients, has not been previously described. METHODS: We review
ed all patients with colorectal perforations caused by irrigation enemas ad
mitted to our sen ice in the three-lear period between January 1995 and Dec
ember 1997. RESULTS: Thirteen patients were treated by our surgical service
because of perforations of the rectum and sigmoid colon related to a previ
ous retrograde irrigation enema. Ten of these patients came from nursing ho
mes, and the other three lived at home. The relevant information relating t
he enema administration to the patient's condition was given in only two of
the ten patients referred to the emergency room by the institution's nursi
ng or medical staff. In the other eight the information was vague and somet
imes misleading. The diagnosis of colorectal perforation tvas made by histo
ry, plain abdominal x-rays, and CT scan with or without medglumine diatrizo
ate enemas. Ten patients survived, regardless of age, previous diseases, or
operative findings. In all of them, diagnosis was made within 36 hours fro
m the perforation. The three deaths occurred in patients in whom the diagno
sis was made late. CONCLUSIONS: Awareness of the possible injury from enema
s administered to chronically constipated patients should be stressed. A hi
gh degree of suspicion by the attending physician is extremely important, b
ecause prompt diagnosis and early surgical treatment curies a relatively go
od prognosis.