Seprafilm (R)-induced peritoneal inflammation: A previously unknown complication - Report of a case

INTRODUCTION: Various substances and agents have been evaluated to prevent postoperative adhesion formation. Recently a sodium hyaluronate-based biore sorbable membrane was introduced with promising clinical results. Its appli cation was regarded as safe and efficient. METHODS: We present the first re ported case of a severe inflammatory reaction to a bioresorbable membrane a nd give a review of the related literature. CONCLUSION: Bioresorbable membr anes are increasingly used by general surgeons and gynecologists to reduce postoperative adhesion formation. Bioresorbable membranes may produce exten sive inflammatory reactions.