Objectives: In order to evaluate the benefit provided through less invasive
surgical techniques for the treatment of multivessel coronary artery disea
se, a prospective clinical trial was started. Methods: Group I included 53
patients (38 males, 15 females, age 51-79 years, mean 62.8 +/- 6.1 years) r
eceiving conventional bypass surgery, group 2 included 69 patients (59 male
, 10 female, age 43-82 years, mean 61.9 +/- 8.6 years) receiving less invas
ive surgical procedure including minithoracotomy in combination with cardio
pulmonary bypass. Results: No perioperative death occurred in the whole ser
ies of patients. Time of operation was 267 +/- 61 min in group 2 and 162.9
+/- 53.6 min in group 1. Intensive Care Unit stay was I day for both groups
and Hospitalization 6.9 +/-: 6.0 for group 1 and 7.5 +/- 2.6 days for grou
p 2. Perioperative bleeding was less in group 2 (P > 0.01). Back and chest
pain assessment on postoperative day 3 showed less pain in group 2 (P < 0.0
5). Three-month follow-up revealed ischemia in stress electrocardiogram in
two patients (3.8%) in group 1 and in 2 patients (2.9%) in group 2. Coronar
y angiograms confirmed the stress ECG findings. There was one (1.4%) redo o
peration in group 2 and two (3.8%) in group 1. Conclusions: Both techniques
are equal efficient. Even though time of operation is longer in patients r
eceiving less invasive procedure, intensive care unit stay and hospitalizat
ion is exactly as long. Patients receiving minimally invasive surgery bleed
less and have less pain early postoperatively. (C) 1999 Elsevier Science B
.V. All rights reserved.