IC1n, an ion channel-forming protein associated with cell volume regulation

Authors
Gschwentner, M Furst, J Ritter, M Bazzini, C Woll, E Dienstl, A Jakab, M Konig, M Scandella, E Rudzki, J Botta, G Meyer, G Lang, F Deetjen, P Paulmichl, M
Citation
M. Gschwentner et al., IC1n, an ion channel-forming protein associated with cell volume regulation, EXP PHYSIOL, 84(6), 1999, pp. 1023-1031
Citations number
43
Categorie Soggetti
Physiology
Journal title
EXPERIMENTAL PHYSIOLOGY
ISSN journal
09580670 → ACNP
Volume
84
Issue
6
Year of publication
1999
Pages
1023 - 1031
Database
ISI
SICI code
0958-0670(199911)84:6<1023:IAICPA>2.0.ZU;2-6
Abstract
It is not resolved whether the anionic channel involved in volume regulatio n after cell swelling comprises one or more subunits. Moreover, it remains to be determined which of the different proteins cloned so far, for which a n involvement in cell volume regulation has been postulated, is the ideal c andidate. In this review, we consider the role of the ICln protein, cloned from MDCK cells, in cell volume regulation.