N. Skammelsrud et al., The gene for human transcription factor TCF11 is located telomeric to D17S1827, BTR and HP1(Hs beta) on chromosome 17q22, GENET A-BIO, 15(6), 1999, pp. 217-222
We report the screening of thirty-one YACs with a number of markers using p
olymerase chain reaction (PCR) to construct a physical map of part of human
chromosome 17q21.3-q22. A contig of YACs covering about 4 Mb was construct
ed around the TCF11 gene at 68 cM from the most telomeric marker on the p a
rm, localizing TCF11 telomeric to genetic marker D17S1827. Both human and m
ouse P1-derived artificial chromosomes (PACs) containing TCF11 were isolate
d and characterized. The human heterochromatin protein 1 gene, HPIHs beta,
and its homologue in mouse, MoMOD1, were identified centromeric to TCF11. (
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